Bed & Breakfast
BED AND BREAKFAST
Breakfast is included with your stay.
Choose a currency for your trip.
No currencies found. Try a name or currency code.
Find your next stay
3253 William StreetView location
Room prices, availability, meal plans and cancellation terms are confirmed for your selected dates.
Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay.
Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing.
Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River.
Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa.
We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable.
We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls.
When you stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Shawnee National Forest and Mississippi River.
This spa hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.4 mi (3.8 km) from Cape Splash Family Aquatic Center. Make yourself at home in one of the 102 guestrooms featuring microwaves and flat-screen televisions. Your pillowtop bed comes with down comforters and premium bedding.
Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers. Featured amenities include complimentary wired internet access, a business center, and complimentary newspapers in the lobby. Planning an event in Cape Girardeau?
This hotel has 118 square feet (11 square meters) of space consisting of conference space and a meeting room. Free self parking is available onsite.
English
Services and fees can vary. Check the selected room details and hotel policies before booking.
Meal options depend on the room and rate you choose. Search your dates to see which meal plans are included.
Bed & Breakfast
BED AND BREAKFAST
Breakfast is included with your stay.
Half Board
Usually includes breakfast and one additional meal.
Room Only
Accommodation only. Meals are usually not included.
Full Board
Usually includes breakfast, lunch, and dinner.
All Inclusive
Meals and selected drinks/services may be included.
These are the hotel's room types, rather than live offers. Choose your travel dates to see available rooms, prices and booking conditions. Check availability
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.KG-3
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.QN
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-KG
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.ST
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.QN-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.DX
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.2Q-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-2Q
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.2Q
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-3
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.QN
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.QN-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.ST-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.KG-1
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.KG-NM
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.KG
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.ST
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.KG
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.ST
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express Suites Cape Girardeau I-55 IHG
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.NM
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
No room types match your search. Try a room name or feature such as a balcony.
What other guests saying about Holiday Inn Express Suites Cape Girardeau I-55 IHG
Nice hotel
Holiday Inn Express Suites Cape Girardeau I-55 IHG
3253 William Street, Cape Girardeau, United States
Compare other stays close to this hotel. Choose travel dates to check availability.