Bed & Breakfast
BED AND BREAKFAST
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4250 Midamerica LaneView location
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Welcome to the new Holiday Inn Express & Suites St. Louis South I-55!
South St. Louis's newest and most modern Holiday Inn Express hotel is nestled within a growing development at the intersection of Butler Hill Road and I-55, just one mile south of I-270/255, with access to everything St. Louis offers.
Located just 14 miles south of downtown St. Louis at exit 195 off I-55, business travelers will benefit from our central location with easy on/off access to I-55, connecting to different areas of St. Louis within minutes. The hotel complex includes the Barnes-Jewish Siteman Cancer Center and Mercy Health.
We are also minutes from MetLife, Anheuser-Busch, Cigna, and the National Cemetery Administration.
Our non-smoking Holiday Inn Express & Suites St. Louis I-55 hotel offers convenient access for guests visiting Busch Stadium, the Gateway Arch, Grant's Farm, the Magic House, the St. Louis Science Center, the St. Louis Zoo, Forest Park, River City Casino, and much more!
Hotel guests can enjoy an array of amenities, including suites, an indoor pool, a Suite Shop, two meeting rooms, a complimentary Express Start breakfast, complimentary high-speed wired and wireless internet, a comfortable Great Room with an outdoor patio, and warm cookies and milk served nightly.
Experience genuine Midwestern hospitality at our South St. Louis location.
Spend an evening in a nice atmosphere of the bar. Taste the local cuisine and have a rest in the restaurant. In the shared kitchen, you can cook anything you want.
Wi-Fi on the territory will help you stay on-line.If you travel by car, you can park in a parking zone. The beauty and wellness services: a massage room, a sauna, a solarium, a spa center and a hamam.
Sports fans will be able to enjoy a gym and a mini-golf area.
For winter sports fans, the following services are available: a ski school, ski facilities rental, ski-to-door access and ski passes.You will find these entertainment amenities on the premises: a casino, a karaoke, a library, a bowling club, a ping-pong area and a barbeque area.
Tourists who can’t live without swimming will appreciate a pool, an aquapark, an indoor pool and an outdoor pool. You can arrange a business meeting, a board meeting, and even a job interview as there is a business center. Want to have an excursion?
Consult the tour assistance desk of the hotel.Accessibility: there is an elevator/lift. Additional services that the hotel offers to its guests: a laundry, an ATM, a chapel, private check-in and check-out, car rental and a safe-deposit box.
A great place to have a rest after an exciting day! Hotel «Holiday Inn Express & Suites St. Louis South - I-55» is located in Dupo. This hotel is located in 13 km from the city center. You can take a walk and explore the neighbourhood area of the hotel.
Places nearby: Barnes Jewish South Campus.
Services and fees can vary. Check the selected room details and hotel policies before booking.
Meal options depend on the room and rate you choose. Search your dates to see which meal plans are included.
Bed & Breakfast
BED AND BREAKFAST
Breakfast is included with your stay.
Buffet Breakfast
This meal plan may be available depending on the selected room/rate.
Half Board
Usually includes breakfast and one additional meal.
Full Board
Usually includes breakfast, lunch, and dinner.
Room Only
Accommodation only. Meals are usually not included.
All Inclusive
Meals and selected drinks/services may be included.
These are the hotel's room types, rather than live offers. Choose your travel dates to see available rooms, prices and booking conditions. Check availability
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.B1-H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.KG-2
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.DX-KG
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.ST-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.2Q
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: QUA.2Q-NM
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.2Q-B1
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-KG
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.NM
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.KG-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.H6-KG
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.KG-3
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.ST
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photo unavailable
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Photo unavailable
Photo unavailable
Photo unavailable
Photo unavailable Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.2B
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: TWN.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.ST
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.2Q-NM
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SGL.ST
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photo unavailable
Photo unavailable
Photo unavailable
Photo unavailable
Photo unavailable
Photo unavailable Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.H6-2Q
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: QUA.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.KG
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.H6-QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.H6-2D
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.KG
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBT.DB
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: QUA.H6-QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.2Q
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: QUA.ST
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: QUA.QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.H6-KG
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.DB
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.KG-NM
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.ST
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBT.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: QUA.H6-2Q
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SGL.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Select a photo to open the full-screen viewer.
Photo unavailable
Photo unavailable
Photo unavailable
Photo unavailable
Photo unavailable
Photo unavailable Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.KG-1
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express and Suites St.Louis South-I-55
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.2Q
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
No room types match your search. Try a room name or feature such as a balcony.
Holiday Inn Express and Suites St.Louis South-I-55
4250 Midamerica Lane, St. Louis, United States
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