Bed & Breakfast
BED AND BREAKFAST
Breakfast is included with your stay.
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601 Main StreetView location
Room prices, availability, meal plans and cancellation terms are confirmed for your selected dates.
We welcome you to stay at our Holiday Inn Express &Suites Buffalo, located in the heart of downtown near Roswell Park, John R. Oishei Children's Hospital, Buffalo General Hospital, Convention Center and Canalside. Hotel parking is available nearby at additional charge in parking garage.
Enjoy being nestled in the heart of the Theatre District, where you can experience a grand performance at Shea's Performing Arts Center or the Irish Classical Theatre.
Take in a concert at the Town Ballroom or TRALF located within the same block or hop on the above ground trolley train to the Key Bank Center. The Seneca Buffalo Creek Casino offers a free shuttle to and from the casino. Explore &More - Ralph C. Wilson Jr.
Children's Museum and the Naval Park are also just a few blocks away. The city is also packed with events and festivals at Canalside and Sahlen's Field. Admire contemporary art at the Albright-Knox Art Gallery or discover Frank Lloyd Wright's stunning residencies nearby and marvel at the Darwin Martin House.
Don't forget to make the 20 mile trip to one of the Nation's North American Wonders of the World - Niagara Falls!For those traveling on business we are in close proximity to M&T Bank, Buffalo Niagara Medical Campus, and New Era Cap.
You will appreciate our 24-hour business center and fitness center. Also located adjacent to the hotel is a TGI Friday’s restaurant.
Services and fees can vary. Check the selected room details and hotel policies before booking.
Meal options depend on the room and rate you choose. Search your dates to see which meal plans are included.
Bed & Breakfast
BED AND BREAKFAST
Breakfast is included with your stay.
Half Board
Usually includes breakfast and one additional meal.
Full Board
Usually includes breakfast, lunch, and dinner.
Room Only
Accommodation only. Meals are usually not included.
All Inclusive
Meals and selected drinks/services may be included.
These are the hotel's room types, rather than live offers. Choose your travel dates to see available rooms, prices and booking conditions. Check availability
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.NM
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.2B
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.KG
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Select a photo to open the full-screen viewer.
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Photo unavailable Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.B1-KG
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.H6-QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.CV-KG
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.B1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.ST-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-WV
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.NM
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.QN
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.KG
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.ST
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.RO
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-QN
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: DBL.ST
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6-1
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.ST
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.B1-H6
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Photos are not available for this room type.
Adult and child limits apply within the room's total guest limit.
Room code: ROO.CV
Limited room details from hotel
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Adult and child limits apply within the room's total guest limit.
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
Check availabilityHoliday Inn Express & Suites Buffalo Downtown
Select a photo to open the full-screen viewer.
Photos illustrate the room type; your assigned room may vary.
Adult and child limits apply within the room's total guest limit.
Room code: SUI.H6
Available rooms, prices and included facilities are confirmed after you choose your dates and rate.
No room types match your search. Try a room name or feature such as a balcony.
Holiday Inn Express & Suites Buffalo Downtown
601 Main Street, Buffalo, United States
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